Advances in DNA Sequence-specific Agents: 4 by B. J. Chapman

By B. J. Chapman

This sequence encompasses layout, synthesis, software, and analytical equipment (including medical and in vitro) for the research of those severe interactions. As our knowing of the genome and proteome expands, common advancements within the box of DNA series particular interplay tend to play an more and more vital position. for this reason, manuscripts were solicited from specialists masking a various diversity of fields, reflecting the cross-disciplinary and dynamic nature of the series.

Volume four describes paintings at the amendment of DNA by means of AT particular anticancer medicinal drugs, DNA alkylation occasions which contain metabolite iteration, DNA series acceptance via selective binders, bulged DNA microenvironments as molecular objectives, DNA series particular binding through brief peptides and the research of DNA-protein interactions utilizing DNase I footprinting methodology.

Features contain:
• professional members from the Biomedical world
• rising components of drug layout and healing applications
• Nucleic acid-protein interactions
• colour pics of molecular modeling analyses
• New and rising methodologies

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